Mary was born about 1748 in Mordecai's Mt., Ware Parish, Gloucester, Virginia, the daughter of unknown parents.
She has died but the date and place are unknown.
Her husband was Thomas Mustain, who she married in ABT 1748 in Pittsylvania, Virginia. Their eleven known children were Jesse (1750-1794), Anna (1750-?), Mary Ann (1752-?), Mildred (1755-?), Avery (1756-?), Molley (1758-?), Rebecca (1760-?), Tabitha (1766-?), Salley (1767-?), Winifred (1768-?) and Saludy (1772-?).